Spectrum of childhood poisoning in a tertiary center in the Eastern Saudi Arabia
نویسنده
چکیده
ungal infection in premature infants is not rare.1 By virtue of their size and increased exposure to interventional methods of care including indwelling lines and catheters, the premature infants in an intensive care unit are prone to develop candidal fungemia. Candida guilliermondii (C. guilliermondii) is among the one of the rare species of candida causing fungemia.2 However, the management of this rare fungemia has been viewed controversially. The risk of not treating a true infection3,4 versus treating a pseudofungemia5,6 with toxic antifungal drugs has been put forward as the arguments. To further highlight on the contradiction in treatment associated with C. guilliermondii, the following case is presented. The infant was born at 28-weeks of gestation with birth weight of 1030 grams. She developed signs of respiratory distress for which she required intubation and mechanical ventilation. A septic work up was carried out and she was started on ampicillin and gentamicin. On the fourth day, she discovered to have a murmur diagnosed as patent ductus arteriosus. The admission blood culture was negative. The infant had a very stormy course. She had several episodes of non-specific symptoms requiring appropriate work-up including several blood cultures. Out of 7 blood cultures, 3 were positive for C. guilliermondii. The first positive blood culture report (day 35) was treated with central line removal. No antifungal treatment was started keeping in view of the relatively rare and uncommon specie of candida with high suspicion of
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تاریخ انتشار 2004